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Can You Really Overdose on Ivermectin? - The Risks and Benefits of this Controversial Treatment Perhaps you’ve heard the word ivermectin being thrown around at your vet’s office, but you don’t know what it means or what it could do to your pet. The truth is that it could save his life—or it could be dangerous and cause serious side effects. This all depends on whether or not your dog actually has heartworms, because ivermectin can be risky if your dog isn’t infected with them.